Japan pharma startup developing world-first drug to grow new teeth

Thu, 9 Nov 2023 11:32:40 +1100

Andrew Pam <xanni [at] glasswings.com.au>

Andrew Pam
<https://www.japantimes.co.jp/news/2023/09/24/japan/science-health/japan-pharma-grows-new-teeth/>

'OSAKA – A team of scientists led by a Japanese pharmaceutical startup has been
working on a drug to stimulate the growth of new teeth in what would be a
world-first, aiming to put it on the market by around 2030.

Toregem Biopharma, funded by Kyoto University, is expected to begin clinical
trials on healthy adults in around July 2024 to confirm the drug's safety,
after the team succeeded in growing new teeth in mice in 2018.

Most people have "tooth buds" that have the potential to become a new tooth, in
addition to baby and permanent teeth, although the buds usually do not develop
and subsequently disappear.

The team created an antibody drug that inhibits the protein that suppresses the
growth of teeth. The drug works on these buds and stimulates their growth.

In 2018, the team also administered the drug to ferrets, which have both baby
and permanent teeth similar to humans, and new teeth grew.'

Via What Could Go Right? October 5, 2023:
https://theprogressnetwork.org/natural-disaster-deaths-declining/

Cheers,
       *** Xanni ***
--
mailto:xanni@xanadu.net               Andrew Pam
http://xanadu.com.au/                 Chief Scientist, Xanadu
https://glasswings.com.au/            Partner, Glass Wings
https://sericyb.com.au/               Manager, Serious Cybernetics

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