World's first tooth-regenerating drug to enter testing in Japan

Thu, 27 Jun 2024 03:44:25 +1000

Andrew Pam <xanni [at] glasswings.com.au>

Andrew Pam
https://archive.md/UHj0P

'KYOTO — A Japanese startup will launch clinical trials in September of what
is believed to be the first-ever treatment that can regrow teeth.
Toregem Biopharma aims to bring the antibody drug to market in 2030 for
patients missing some or all of their teeth from birth — a condition known as
congenital anodontia. The Kyoto University-affiliated startup hopes to
eventually offer it to those who lose teeth later in life as well. It announced
the clinical trials Thursday.

The antibody targets a specific protein that inhibits tooth growth. Tested in
such animals as mice, it stimulated the development of tooth buds in the jaw,
causing new teeth to form.

People with congenital anodontia, which affects an estimated 0.1% of the
population, typically get implants or dentures in adulthood. No treatment
currently addresses the condition's root cause.

"We want to make this a third option," said Toregem co-founder Katsu Takahashi,
whose research the drug is based on.'

Via Fix the News:
<https://fixthenews.com/good-news-global-life-expectancy-domestic-violence-australia-emissions-china/>

Cheers,
       *** Xanni ***
--
mailto:xanni@xanadu.net               Andrew Pam
http://xanadu.com.au/                 Chief Scientist, Xanadu
https://glasswings.com.au/            Partner, Glass Wings
https://sericyb.com.au/               Manager, Serious Cybernetics

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