https://archive.md/PZnDL
"Half a decade ago, chemist Mark Levin was a postdoc looking for a visionary
project that could change his field. He found inspiration in a set of published
wish lists from pharmaceutical-industry scientists who were looking for ways to
transform medicinal chemistry. Among their dreams, one concept stood out: the
ability to precisely edit a molecule by deleting, adding or swapping single
atoms in its core.
This sort of molecular surgery could dramatically speed up drug discovery — and
might altogether revolutionize how organic chemists design molecules. One 2018
review called it a ‘moonshot’ concept. Levin was hooked.
Now head of a team at the University of Chicago in Illinois, Levin is among a
cadre of chemists pioneering these techniques, aiming to more efficiently forge
new drugs, polymers and biological molecules such as peptides. In the past two
years, more than 100 papers on the technique — known as skeletal editing — have
been published, demonstrating its potential (see ‘Skeletal editing on the
rise’). “There’s a tremendous amount of buzz right now around this topic,” says
Danielle Schultz, director of discovery-process chemistry at pharmaceutical
company Merck in Kenilworth, New Jersey."
Via
Future Crunch:
<
https://futurecrunch.com/good-news-inequality-aids-south-africa-tortoises-galapagos/>
Cheers,
*** Xanni ***
--
mailto:xanni@xanadu.net Andrew Pam
http://xanadu.com.au/ Chief Scientist, Xanadu
https://glasswings.com.au/ Partner, Glass Wings
https://sericyb.com.au/ Manager, Serious Cybernetics
